Domino’s Italian Sandwich Recipe

One of the crowd favorites among Domino’s sandwiches, Domino’s Italian sandwich combines a combination of cured meats, provolone cheese, and peppers in a soft Italian bread. The cured meats and provolone are really what bring the Italian food flavor in it. Assemble this super simple Italian sub and have a fast food meal made at home ready in just 15 minutes! Make it a complete lunch set with a side of caprese salad and a raspberry iced tea.

preparing the domino's italian sandwich

Tips on Making Domino’s Italian Sandwich

What’s on Domino’s Italian sandwich? It’s mainly salami, lyoner, pepperoni, peppers, and provolone layered up in a buttered toasted Italian bread. But of course, you can always customize this Italian sandwich recipe according to your preference and ingredient availability. Here are tips on making it:

  • Use any soft and crusty bread roll that is sturdy enough to hold all the fillings in like hoagie rolls or baguette. You can scrape off some of the bread from the top layer to make more room for filling. 
  • Slice the bread neatly using a serrated bread knife. It’s also easier to slice if it’s chilled.
  • For the meat, genoa salami and pepperoni give excellent flavor. But you can also use smoked ham, roast meat, or turkey pepperoni for something healthier. About 12 oz of meat for every bread roll makes a good meat to bread ratio. This makes the sandwich easy to handle and also gives you a good taste of everything. But you can fill it as much as you want.
  • Provolone is the top choice for cheese, but you can use any melting cheese like American cheese, Swiss, or mozzarella cheese.
  • Add other delicious sandwich toppings to your sub. You can smear pesto sauce on the bread and add banana peppers, sun dried tomatoes, and a dash of black pepper for more flavor. Piquillo peppers are red or green peppers that offer flavor without much heat, but if you want it spicy, you can add chili flakes. Lettuce and ripe tomato slices will add a fresher taste, but remember to add these fresh ingredients only after baking.
  • Make your homemade Domino’s subs ahead. To store, cool them to room temperature then wrap them with plastic wrap. Reheat them in the microwave or on the stove top.

Looking for other Italian sandwiches to make? Check out this Mediterranean veggie sandwich which has hummus, feta, cucumber, tomatoes, and red onion. On the other hand, this version of the Italian sub sandwich contains mortadella, capicollo, mayonnaise, and banana peppers.

Domino’s Italian Sandwich Recipe

How To Make Domino's Italian Sandwich

Easily recreate Domino’s Italian sandwich at home in just 20 minutes! It’s got salami, pepperoni, lyoner, and provolone on buttered bread all baked together until slightly crisp.

Prep: 9 mins
Cook: 10 mins
Total: 19 mins


  • oz pepperoni slices
  • oz lyoner, thinly sliced
  • 3 oz Salami, thinly sliced
  • 1 cup red onions
  • ½ cup piquillo peppers
  • ½ cup red or yellow bell peppers
  • 7 oz Provolone cheese, grated
  • 1 Italian sub bread
  • ¼ cup unsalted butter, melted


  1. Preheat oven to 350 degrees F.
  2. Slice your bread lengthwise & brush evenly the insides with melted butter.
  3. Assemble sandwiches by layering pepperoni, ham, salami, onions, piquillo peppers, red bell peppers, and provolone cheese.
  4. Bake for 10 minutes until cheese is melted and bread is toasted.
  5. Seal up and carefully fold your sandwich. You may slice the sandwich into your preferred portions before serving.


  • Sugar: 154g
  • :
  • Calcium: 1597mg
  • Calories: 5000kcal
  • Carbohydrates: 270g
  • Cholesterol: 531mg
  • Fat: 366g
  • Fiber: 20g
  • Iron: 18mg
  • Monounsaturated Fat: 112g
  • Polyunsaturated Fat: 44g
  • Potassium: 2649mg
  • Protein: 153g
  • Saturated Fat: 186g
  • Sodium: 7908mg
  • Trans Fat: 4g
  • Vitamin A: 6843IU
  • Vitamin C: 180mg
Nutrition Disclaimer

Frequently Asked Questions

Can I freeze my Domino’s Italian sandwich?

Yes, you can freeze the sandwiches to make them last longer. Make sure to cool them to room temperature first before wrapping them in plastic wrap. You can reheat them from frozen in the microwave for 2 minutes on High or until heated through. If you will use the oven or the stove, it’s better to thaw them overnight in the fridge first. If you will freeze the sandwiches, make sure not to fill them with fresh vegetables which turn mushy later on. You can add them after reheating instead.

Why is my sub sandwich soggy?

The sandwich becomes soggy if you use ingredients that are too watery like tomatoes and too much sauce. Also, if you store them for too long in the fridge, the bread will eventually soak up moisture from the meat making it soggy.

Sandwich Recipes


We have already cracked the code for the famous Domino’s Italian sandwich for you to make at home. It’s just as delicious, if not more, than the original one. Feel free to serve it at parties, potlucks, or stock them up in the fridge for quick snacks that you can grab anytime.
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