Penne Pasta with Roasted Butternut Squash and Ham Recipe

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Heidi Hernandez Modified: March 21, 2022
Penne Pasta with Roasted Butternut Squash and Ham Recipe

How To Make Penne Pasta with Roasted Butternut Squash and Ham

Sweet and savory flavors from the roasted butternut squash and ham amplifies this rich and filling penne pasta! Whip up a serving in just under an hour.

Preparation: 15 minutes
Cooking: 30 minutes
Total: 45 minutes



  • 1butternut squash,(about 2 lbs)
  • 2tbspolive oil
  • 1tspsalt
  • tspfresh ground black pepper
  • tspdried sage
  • 1cupmascarpone cheese
  • ½cuphalf and half
  • 3scallions,including green tops
  • ¾lbspenne
  • ¼lbsmoked ham,sliced
  • ¼cupgrated parmesan


  1. Heat the oven to 450 degrees F.

  2. Put the squash on a large baking sheet and toss with the oil, ¼ teaspoon of the salt, the pepper and sage. Spread the squash out in a single layer.

  3. Roast, turning occasionally, for 15 to 20 minutes, until tender and starting to brown.

  4. In a small bowl, stir together the mascarpone, half-and-half, scallions and the remaining ¾ teaspoon of salt

  5. In a large pot of boiling, salted water, cook the penne for about 13 minutes, until just done. Reserve 1 cup of the pasta-cooking water and drain.

  6. Return the pasta to the hot pan. Stir in the squash, mascarpone sauce, and ham. If the sauce seems too thick, add some of the reserved pasta-cooking water.

  7. Serve topped with the Parmesan, and enjoy!


  • Calories: 743.69kcal
  • Fat: 34.31g
  • Saturated Fat: 16.16g
  • Monounsaturated Fat: 12.06g
  • Polyunsaturated Fat: 2.33g
  • Carbohydrates: 85.74g
  • Fiber: 5.87g
  • Sugar: 8.50g
  • Protein: 25.36g
  • Cholesterol: 86.45mg
  • Sodium: 823.74mg
  • Calcium: 293.85mg
  • Potassium: 850.61mg
  • Iron: 2.78mg
  • Vitamin A: 928.76µg
  • Vitamin C: 28.88mg
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